Prediction of Maxillary Bone Invasion in Hard Palate/Upper Alveolus Cancer: A Multi-Center Retrospective Study

Background: maxillary bone invasion (MBI) is not uncommon in hard palate or upper alveolus (HP/UA) cancer; however, there have been relatively few reports about the MBI of HP/UA cancer. Patients and Methods: this was a multi-center retrospective study, enrolling 144 cases defined by surgical pathology radiology follow-up. The multiple prediction models for were developed total having primary resection, using clinical radiological variables. Results: computerized tomography (CT) alone predicted MBI, with an area under receiver operating curve (AUC) 0.779 (95% confidence interval (CI) = 0.712–0.847). AUC increased model that combined tumor dimensions factors (male sex nodal metastasis) (0.854 (95%CI 0.790–0.918)). In patients who underwent 18fluorodeoxyglucose positron emission tomography/CT (PET/CT), discrimination performance including maximal standardized uptake value (SUVmax) had 0.911 0.847–0.975). scoring system CT finding, dimension, factors, with/without PET/CT SUVmax clearly distinguished low-, intermediate-, high-risk groups MBI. Conclusion: information from CT, value, cancer can be high performance.